13 results
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... polyangiitis), MPA (microscopic ... Syndromes (PRS) ... feature, PRS can affect ... : • U/A: microscopic
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... Leukocytoclastic Vasculitis Secondary ... Associated: - Microscopic ... Disease • Cogan syndrome ... #dermatology #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
cases • Sjögren syndrome ... Vasculitis: • Microscopic ... polyangiitis without renal ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Restrictive lung defect ... Demyelinating syndromes ... Abdominal pain (20%) Renal ... signs #symptoms #diagnosis ... #rheumatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... cataracts, and renal ... Grey Platelet Syndrome ... #differential #diagnosis ... #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Type III Often Secondary ... Labs/Diagnosis: ... vasculitis - GPA, EGPA, microscopic ... Cryoglobulins #diagnosis ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... PR3-ANCA): • Microscopic ... Dx: GPA, EGPA, microscopic ... • Urinalysis (Renal ... #rheumatology #
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... • Affects 1:25,000 ... late adulthood • Diagnosis ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
dyscrasias • Secondary ... Manifestations: Renal ... : • Nephrotic syndrome ... Carpal tunnel syndrome ... polarized light microscopy