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diagnosis differential nephrology syndromes acute aki ana anca antibody antineutrophil antinuclear bloodsmear borrelia classification clinical diseases hematology hematuria kidneyinjury management
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
cells on urine microscopy ... RBCs and/or RBC casts ... • Anti-GBM antibodies ... with polyangiitis/microscopic ... #Causes
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... sediment - WBC/RBC casts ... • Anti-GBM antibodies ... polyangiitis (GPA) / microscopic ... #Causes
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
• Hepatorenal syndromes ... Epithelial cell casts ... Glomerulonephritis • Anti-GBM antibodies ... polyangiitis /microscopic ... #Causes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... #diagnosis #rheumatology
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Northeast Africa with cases ... Several cases have ... Syndrome: 3d of ... and convalescent antibodies ... recurrentis #BloodSmear #microscopy
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... EGPA) • Auto-antibodies ... Goodpasture's cause ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age • 22 and 45 cases ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... tract, and often causes ... Dx: GPA, EGPA, microscopic ... C-ANCA) pattern: antibodies ... differential #diagnosis #rheumatology
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