9 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... cases • Sjögren syndrome ... Vasculitis: • ... Microscopic polyangiitis ... Renal-limited vasculitis
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- Vasculitis, e.g ... granulomatosis p-ANCA ... - Vasculitis, e.g ... Microscopic polyangiitis ... #rheumatology #antibodies
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... vasculitis (Eosinophilic ... polyangiitis, Microscopic ... vasculitis, Behcet ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... ): • Microscopic ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic ... ) pattern: antibodies
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... • ANCA Associated ... : - Microscopic ... Disease • Cogan syndrome ... #rheumatology #differential
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM ... Abdominal compartment syndrome ... • Cardio-renal syndrome
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Using fluorescence microscopy ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... rheumatology #diagnosis #differential
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... vasculitis (AAV ... polyangiitis), MPA (microscopic ... EGPA) • Auto-antibodies ... FINDINGS: • U/A: microscopic
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... )): Microscopic ... • Cogan syndrome ... #Differential #