8 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... polyangiitis, Microscopic ... vasculitis, Behcet ... testing: anti-ANCA ... #Syndrome #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... • Sjögren syndrome ... Vasculitis: • ... Microscopic polyangiitis ... vasculitis - MPO
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... pulmonary and renal ... ): • Microscopic ... Dx: GPA, EGPA, microscopic ... • Urinalysis (Renal
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM ... Abdominal compartment syndrome ... syndrome: troponin
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria - Differential ... urine sediment Microscopic ... hematuria: - RBC casts ... Diagnostic of GN or vasculitis ... #Hematuria #Differential
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
vasculitis (AAV ... polyangiitis), MPA (microscopic ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts ... #Syndromes #differential
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Injury (AKI) - Differential ... at least 50% Renal ... • Hepatorenal syndromes ... Obstruction • Cast ... polyangiitis /microscopic
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... pulmonary and renal ... Differential Diagnosis ... )): Microscopic ... #Differential #