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diagnosis nephrology causes algorithm rheumatology acute aki ana anca antibody antineutrophil antinuclear blood bloodsmear borrelia classification clinical diseases fever hematuria
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Hematuria - Differential ... urine sediment Microscopic ... urine sediment by microscopy ... hematuria: - RBC casts ... #Hematuria #Differential
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Injury (AKI) - Differential ... at least 50% Renal ... • Hepatorenal syndromes ... Glomerulonephritis • Anti-GBM antibodies ... polyangiitis /microscopic
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... tubulointerstitial nephritis, renal ... Fatty - Nephrotic syndrome ... #Differential # ... Microscopy #Diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... • Fanconi's syndrome ... sediment - WBC/RBC casts ... • Anti-GBM antibodies ... polyangiitis (GPA) / microscopic
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... EGPA) • Auto-antibodies ... hematuria, RBC casts ... #Syndromes #differential ... #diagnosis #management
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
resolved after 2-3d ... Several cases have ... Syndrome: 3d of ... and convalescent antibodies ... recurrentis #BloodSmear #microscopy
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... PR3-ANCA): • Microscopic ... Dx: GPA, EGPA, microscopic ... C-ANCA) pattern: antibodies ... • Urinalysis (Renal
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
thrombocytopenia, and renal ... falciparum: Most cases ... tests of liver and renal ... dipstick test, microscopic ... Fever #Travel #Differential
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