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diagnosis differential vasculitis ana antinuclear diseases management acute aki algorithm antibody antineutrophil associations autoantibodies bloodsmear borrelia causes clinical cryoglobulinemia cryoglobulins
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... #diagnosis #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Graves' disease c-ANCA ... granulomatosis p-ANCA ... Microscopic polyangiitis ... diagnosis #table #rheumatology ... #antibodies
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... small vessels - ANCA-associated ... granulomatosis - microscopic ... dermatomyositis #Size #Classification ... Vessels #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... Dx: GPA, EGPA, microscopic ... ) pattern: antibodies ... differential #diagnosis #rheumatology ... #classification
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... polyangiitis), MPA (microscopic ... EGPA) • Auto-antibodies ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
at least 50% Renal ... • Hepatorenal syndromes ... Epithelial cell casts ... Glomerulonephritis • Anti-GBM antibodies ... polyangiitis /microscopic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Using fluorescence microscopy ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #rheumatology #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... DDX: • ANCA (Antineutrophil ... vasculitis - GPA, EGPA, microscopic ... diagnosis #types #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Diagnosis: • ANCA-associated ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... 1, SCL-70, RNP antibodies
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... )): Microscopic ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
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