9 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... antibodies #diagnosis #rheumatology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Pauci-Immune: - ANCA-positive ... polyangiitis, Microscopic ... testing: anti-ANCA ... #diagnosis #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine sediment Microscopic ... urine sediment by microscopy ... pain hematuria syndrome ... hematuria: - RBC casts ... causes #urology #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... Glomerulonephritis / Vasculits: ANCA ... Abdominal compartment syndrome ... syndrome: troponin ... Differential #Diagnosis #nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
tubulointerstitial nephritis, renal ... Fatty - Nephrotic syndrome ... edgarvlermamd - Nephrology ... #Differential #Microscopy ... #Diagnosis #Nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... ): • Microscopic ... Dx: GPA, EGPA, microscopic ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
at least 50% Renal ... • Hepatorenal syndromes ... Epithelial cell casts ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... polyangiitis), MPA (microscopic ... Auto-antibodies: ANCA ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... )): Microscopic ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology