28 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine • 1ml blood ... basement membrane disease ... - Alport syndrome ... of glomerular disease ... #renal #urine #blood
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... and Associated Diseases ... Morphologies #Key #Atlas #Microscopy ... #Pathology #Hematology ... Pathologic Basis of Disease
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... cells: Sickle cell disease ... #Peripheral #Blood ... Smear #Analysis #hematology ... #microscopy #interpretation
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
granulomatosis - microscopic ... Churg-Strauss syndrome ... - Schnitzler syndrome ... - Sjögren syndrome ... Vessels #Diagnosis #Rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Microscopic polyangiitis ... Goodpasture's syndrome ... diagnosis #table #rheumatology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... Advanced kidney disease ... Red blood cell ... Fatty - Nephrotic syndrome ... #Differential #Microscopy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
• Sjögren syndrome ... connective tissue disease ... Vasculitis: • Microscopic ... antibodies #diagnosis #rheumatology ... #diseases
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... anemia, Chronic disease ... , McLeod blood group ... differential #diagnosis #hematology ... #microscopy #atlas
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Associated: - Microscopic ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... Vasculitis #skin #dermatology ... #rheumatology #