13 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... cells: Sickle cell ... #Smear #Analysis ... #hematology #microscopy
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... non-specific red cell ... #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... develop leukostasis syndrome ... • Peripheral smear ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... abnormal under the microscope ... abnormal under a microscope ... smear • Bone marrow ... #oncology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Microangiopathic Hemolytic ... differential #diagnosis #hematology ... #microscopy #atlas
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Peripheral smear ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell ... - Peripheral Blood ... Smear ↑ abnormal
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... sensitize red blood ... #anemia #hematology
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
on Peripheral Blood ... Smear 23M Somali ... resolved after 2-3d ... Syndrome: 3d of ... recurrentis #BloodSmear #microscopy
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... general feeling of ill ... : - Biopsy - Microscopic ... neutrophils in the blood ... #dermatology #oncology