23 results
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
cold agglutinin disease ... individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
cold agglutinin disease ... individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... and Associated Diseases ... Morphologies #Key #Atlas #Microscopy ... #Pathology #Hematology ... Pathologic Basis of Disease
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
patient with McLeod Syndrome ... expression of Kell RBC ... granulomatous disease ... #Smear #Pathology ... #Microscopy #Clinical
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... cells: Sickle cell disease ... #Smear #Analysis ... #hematology #microscopy
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Electrolytes: Wilson's disease ... - Peripheral Blood ... Smear ↑ abnormal
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology ... , McLeod blood group ... differential #diagnosis #hematology ... #microscopy #atlas
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine • 1ml blood ... basement membrane disease ... hematuria: - RBC ... of glomerular disease ... #renal #urine #blood
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal Blood ... Smear • Drugs ... Neutrophils - Low RBC ... Pernicious Anemia RBCs ... Myelodysplastic Syndromes
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... La) - Sjogren's syndrome ... Microscopic polyangiitis ... Goodpasture's syndrome ... diagnosis #table #rheumatology