13 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine • 1ml blood ... urine sediment Microscopic ... Diagnostic of GN or vasculitis ... microscopic and ... #renal #urine #blood
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... • Sjögren syndrome ... ANCA-Associated Vasculitis ... : • Microscopic ... #diagnosis #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Microscopic polyangiitis ... diagnosis #table #rheumatology ... #antibodies
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... tract, and often causes ... Dx: GPA, EGPA, microscopic ... C-ANCA) pattern: antibodies ... differential #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Infection - Vasculitis ... Sjogren's, GPA, EGPA, Microscopic ... : • Complete blood ... • Fecal occult blood
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Investigations: full blood ... dipstick, urine microscopy ... osmolarity If cause ... Glomerulonephritis / Vasculits ... screen, including blood
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Hyperviscosity Syndrome ... - GPA, EGPA, microscopic ... classification #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... (inflamed blood ... rash #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... polyangiitis), MPA (microscopic ... EGPA) • Auto-antibodies ... reveals increasing blood ... FINDINGS: • U/A: microscopic