14 results
Raynaud's Phenomenon on Physical Exam

#Raynauds #Syndrome #disease #phenomenon #clinical #video #physicalexam #fingers #hands #rheumatology
Raynaud's Phenomenon ... #Syndrome #disease ... #phenomenon #clinical ... #video #physicalexam ... fingers #hands #rheumatology
Raynaud's Syndrome - Washing off under hot water.
Raynaud phenomenon is an exaggerated vasoconstrictive response of the
Raynaud's Syndrome ... #Raynauds #Syndrome ... #disease #phenomenon ... #clinical #video ... fingers #hands #rheumatology
Raynaud's Syndrome - Washing off under hot water wath.

Raynaud phenomenon is an exaggerated vasoconstrictive response of
Raynaud's Syndrome ... #Raynauds #Syndrome ... #disease #phenomenon ... #clinical #video ... fingers #hands #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... Microscopic polyangiitis ... Goodpasture's syndrome ... diagnosis #table #rheumatology ... #antibodies
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... likely it will be clinically ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... cases • Sjögren syndrome ... Vasculitis: • Microscopic ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... reticularis • Raynaud ... hemolytic #anemia #hematology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... with MCTD and Raynaud's ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
hypofunction • Antibodies ... • Antinuclear antibodies ... salivary ducts Clinical ... Cryoglobulinemia (4%-12%), Raynaud ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic ... C-ANCA) pattern: antibodies ... differential #diagnosis #rheumatology