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diagnosis management aplastic causes classification abscess aflp algorithm apml bandemia cancer cbc comparison differentiation erythematosus fatty hematololgy hepatology hodgkins hypertension
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... vs Hypocellular MDS ... #diagnosis #oncology ... #hematololgy
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... common • Imaging: CXR ... - pulmonary opacities ... initiation • Differential ... #oncology
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... Pulmonary arterial ... Chronic hemolytic anemia ... multifactorial mechanisms Hematologic ... Classification #Diagnosis #Differential
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... likelihood of negative clinical ... #differential # ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelets) • MDS ... precursors MDS ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Leukocytosis, anemia ... Lung #Abscess #pulmonary ... #differential #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential ... Maternal Support - Critical ... Liver #Pregnancy #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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