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diagnosis hematology oncology algorithm differential management workup mds pancytopenia chronic cll cord gravis leukemia lymphocytic myasthenia myelodysplasia spinal spinalcord syndromes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Constitutional Syndromes ... • Hypocellular myelodysplastic ... syndrome (MDS)
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... group of disorders ... platelets) • MDS ... • Aplastic Anemia ... Neutropenia • Platelet Disorders
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... #Syndrome #MDS
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
HLH syndrome 5. ... Eating disorders ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
HLH syndrome 5 ... Eating disorders ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... distribution in the 30s ... test - Cogan sign ... - Peek sign ... diagnosis #management #neurology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... lymphoproliferative disorders ... • Neutropenia, anemia ... Pure red cell aplasia ... • Richter’s Syndrome
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... • Symptoms and signs ... findings of: - Spastic ... MCTD, Sjogren syndrome ... #diagnosis #neurology
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