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diagnosis differential management anemia aplastic apml biliary cholangitis cirrhosis classification differentiation dili disorders drug gastroenterology hematololgy idiosyncratic induced injury liver
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Definition • Pathophysiology ... Expectation • Rx Algorithm ... Anemia #diagnosis #oncology ... #hematololgy
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
dependent injury (ie ... ongoing ↑ LFTs or symptoms ... liver disease 6-9 ... gastroenterology #algorithm ... gastroenterology #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
• Female:Male 9: ... 65 years PBC Pathophysiology ... PBC Signs and Symptoms ... up to 70% • IgM ... diagnosis #workup #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis ... #differential #algorithm
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... diagnosis #management #hematology ... #oncology
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