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diagnosis algorithm hypercalcemia causes adrenalmass calcium acromegaly benign elevated evaluation highcalcium hypertension indications malignant management pathophysiology secondary treatment
Hypercalcemia Workup and Differential Diagnosis Framework 1) Determine whether PTH-dependent 2) Assess for other hormonal causes 3) Assess for
Hypercalcemia Workup ... and Differential ... Assess for non-hormonal ... #Workup #Differential ... Diagnosis #algorithm #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Differential Diagnosis ... PTH: • Elevated Calcitriol ... Cholecalciferol - Excess ... #Differential # ... Algorithm #causes #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Differential Diagnosis ... D Related • Excess ... Vitamin D/Calcitriol ... #Differential # ... Diagnosis #Algorithm #Endocrinology
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Parathyroid hormone–dependent ... humoral syndromes Excess ... #Causes #Differential ... #Diagnosis #Endocrinology
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 Benign Adrenal Mass - Differential Diagnosis Algorithm Hyperplasia - Often Bilateral • Congenital Adrenal Hyperplasia • ACTH
Adrenal Mass - Differential ... High Plasma E2 +Clinical ... Hypertension +/- Hypokalemia ... AdrenalMass #Benign #Differential ... Diagnosis #Algorithm #Endocrinology
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... #workup #differential ... #diagnosis #endocrinology ... elevated #evaluation #workup
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
and Differential ... 109 mm Hg) with clinical ... bruit or signs of hormonal ... excess or hypokalaemia ... Vasculitis • Endocrinologic
Malignant Adrenal Mass - Differential Diagnosis Algorithm Suggestive of Malignancy: Inhomogenous Density, Delay in CT Contrast Washout
Adrenal Mass - Differential ... High Plasma E2 + Clinical ... Hypertension +/- Hypokalemia ... AdrenalMass #Malignant #Differential ... Diagnosis #Algorithm #Endocrinology
Causes of Hypocalcemia by Clinical Cause Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
by Clinical Cause ... or parathyroid hormone ... absent parathyroid hormone ... #Causes #Differential ... #Diagnosis #Endocrinology
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 Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... - If GH excess ... Differential Diagnosis ... Diagnosis and Workup ... Diagnosis #Management #Endocrinology
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