10 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... Pathogenesis and clinical ... GH excess prior ... GH excess after ... signs #symptoms #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth Hormone ... (GH) Growth Hormone ... excess: - ... Giantism or acromegaly ... #FeedbackLoop #endocrinology
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... over-secretion of growth hormone ... (GH) from the pituitary ... #Acromegaly #Signs ... Symptoms #Diagnosis #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... GrepMed Handbook Clinical ... excess occurs before ... islet cell tumor, excess ... Diagnosis #Management #Endocrinology
Acromegalic Hand: Markedly enlarged hand resulting from excess growth hormone. For reference
purposes, the comparison hand is
Acromegalic Hand ... resulting from excess ... growth hormone. ... UCSD Catalog of Clinical ... Images #Clinical
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Clinical Effects ... pituitary apoplexy) Hormone ... excess • Hyperprolactinaemia ... Hypogonadism • Acromegaly ... Symptoms #Diagnosis #Endocrinology
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Puberty Onset • GH ... Excess • Hyperthyroidism ... Resistance • Acromegaly ... Diagnosis #Algorithm #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pathogenesis and Clinical ... common), growth hormone ... ) the anterior hormones ... following order; GH ... #SideEffects #endocrinology
Acromegaly Testing Algorithm
INDICATIONS FOR TESTING:
 • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing ... load • Growth Hormone ... (GH) test (2 hours ... ARUPConsult @ARUPLabs #Acromegaly ... Algorithm #diagnosis #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
109 mm Hg) with clinical ... bruit or signs of hormonal ... excess or hypokalaemia ... Vasculitis • Endocrinologic ... Cushing's syndrome, Acromegaly