20 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... Pathogenesis and clinical ... GH excess prior ... GH excess after ... • Other rare causes
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth Hormone ... (GH) Growth Hormone ... /Symptoms: • GH ... excess: - ... #FeedbackLoop #endocrinology
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... over-secretion of growth hormone ... (GH) from the pituitary ... Symptoms #Diagnosis #Endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
PTH: • Elevated Calcitriol ... Cholecalciferol - Excess ... Diagnosis #Algorithm #causes ... #endocrinology
Differentiation of Causes of Hyperthyroidism According to Pattern of Radionucleotide Uptake
Reduced uptake:
 • Thyroiditis
 • Exogenous
Differentiation of Causes ... Ectopic thyroid hormone ... Graves' disease • Excess ... thyroid-stimulating hormone ... hyperthyroidism #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pathogenesis and Clinical ... For pituitary masses ... following order; GH ... Headaches • Nausea ... #SideEffects #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... excess occurs before ... islet cell tumor, excess ... or refractory cases ... Diagnosis #Management #Endocrinology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Parathyroid hormone–dependent ... humoral syndromes Excess ... Hypercalcemia #Causes ... Differential #Diagnosis #Endocrinology
Hyperthyroidism - Differential Diagnosis Algorithm
High/Normal Radioiodine Uptake
 - Autoimmune Thyroid Disease:
    • Grave's
Goiter - TSH/HCG Excess ... Exogenous/Ectopic Hormone ... Diagnosis #Algorithm #endocrinology ... #causes
Weight Gain / Obesity  - Differential Diagnosis Algorithm
Decreased Expenditure:
 • Sedentary Lifestyle
 • Smoking Cessation
Hypogonadism • GH ... Iatrogenic: • Drugs/Hormones ... Diagnosis #Algorithm #endocrinology ... #causes