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hematology diagnosis oncology differential causes thrombocytosis apl aplastic auer auerrods bloodsmear chronic clinical cll lymphocytic management mds microscopy myelodysplasia myelodysplastic
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Chronic Myelogenous Leukemia ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... - infiltrates (anemia ... , thrombocytopenia ... lymphoid organs When Cancer ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... , thrombocytopenia ... workup #oncology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hematologic: Acute blood ... hemolysis, deficiency anemia ... Malignancy: Metastatic cancer ... Differential #Diagnosis #Algorithm
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... 6.8 g/dL), and thrombocytopenia ... bilobed nuclei, fine ... her peripheral blood ... Path #BloodSmear #Blood
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 Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... IDUS) • Immune Thrombocytopenia ... Syndromes #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... infections/fevers • Thrombocytopenia ... virus (EBV) • Leukemia ... result from low blood ... #oncology #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
current treatment algorithm ... From Blood Cancer ... acute myeloid leukemia ... disease tolerate anemia ... #algorithm #hematology
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