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hematology hemeonc oncology amiodarone apml cell differential differentiation emergencies hemophagocytic histiocytosis hlh induced infections intermittent langerhans lch leukostasis lung lymphohistiocytosis
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... : High spike and ... Non-Infectious Causes ... in AM > PM) • ... • Hyper-IgD syndrome
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... Epidemiology 1) High ... symptoms are not caused ... mediators such as ... : ACUTE, fever,
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC count cause ... - 80% have fever ... acute limb ischemia ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Attempt if high ... : • Common: fever ... Imaging: CXR- pulmonary ... #management #hematology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
respiratory distress syndrome ... associated with high ... Fever 4. ... been reported as ... #diagnosis #management
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
allopurinol 300 mg BID ... Treat underlying cause ... : - Seen with AML ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Lymphohistiocytosis (HLH) High ... caused by uncontrolled ... or triggers) is crucial ... (often termed MAS-HLH ... - Persistent high
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
now classified as ... Multisystem (High ... Smoking cessation is crucial ... in pulmonary LCH ... #Management
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