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symptoms differential antibodies arthritis classification erythematosus lupus ra rheumatoid sle systemic ana anca antibody antineutrophil antinuclear associations autoantibodies autoimmune behcet
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Associations ANA ... c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... #diagnosis #table ... #rheumatology #
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... , Rheumatoid Vasculitis ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... • Cogan Syndrome ... purpura: strong sign ... LFT • ESR • ANA ... #rheumatology #
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
cases • Sjögren syndrome ... ANCA-Associated Vasculitis ... Renal-limited vasculitis ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... ) Differential Diagnosis ... Glucocorticoids 5-ASA ... #signs #symptoms ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
endothelial injury and end-organ ... • Autoimmune diseases ... Labs/Diagnosis: ... Cryoglobulins #diagnosis ... classification #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... • Cogan syndrome ... #Rheumatology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
polymorphisms alter ... galactose-deficient IgA1 (GD-IgA1 ... nephrotic/nephritic syndrome ... Pathophysiology #Diagnosis ... #Signs #Symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... ANCA-associated vasculitis ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis ... #Rheumatology
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