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rheumatology lupus sle differential ana antibodies antibody antineutrophil antinuclear classification criteria diseases management nephrology pulmonary renal slicc summary syndrome vasculitides
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... lupus erythematosus ... Anti-Ro/SSA ... Jcortesizaguirr #ANA ... Antineutrophil #antibodies #diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Pauci-Immune: - ANCA-positive ... Immune Complex: Systemic ... lupus erythematosus ... , anti-GBM ab, ANA
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease & renal ... activity Anti-Ro ... #SLE #Summary #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
laboratory findings (ANA ... : • ANCA-associated ... artery or vein ... Serositis Labs: • ANA ... antibodies • (-) ANA
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... ischemia - Skin: erythematous ... gastrointestinal, and/or central ... lupus erythematosus ... LFT • ESR • ANA
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... - SEROSITIS - RENAL ... IMMUNOLOGIC CRITERIA - ANA ... determined by Positive
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