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differential causes dermatology management oncology activetb generalized latenttb leukemia pruritus tb tuberculosis atopic atopy cll common cvid dermatitis eczema hypogammaglobulinemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Algorithm Decreased ... Hypersplenism • Secondary ... RA, SLE, PRV, Chronic ... Inflammation • Cancer ... #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Chronic ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
metastases Treatment ... - Conduction system ... - Cytopenias (anemia ... #diagnosis #oncology ... #cancer #malignancy
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... • Infections: Chronic ... #Algorithm #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Algorithm - Systemic ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Pruritus #primary #secondary ... #Diagnosis #Algorithm
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... Lymphoma or other cancers ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... hypogammaglobulinemia #immunology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... renal failure/uremia ... #Pruritus #secondary ... #systemic #generalized ... #Diagnosis #Algorithm
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Leukemia - Summary Cancer ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... • Bone pain, dyspnea ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Silicosis • Chronic ... Lymphoma • Lung cancer ... miliary TB Secondary ... hemoptysis • Dyspnea ... malignancy, and chronic
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