9 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... #Acute #Chronic ... #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Supportive with treatment ... liver failure ... Hepatobiliary #hepatology ... #hepatitis #differential ... #diagnosis
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Heart failure ... - Alcoholic hepatitis ... fibrosis - Acute ... peritonitis - Eosinophilic ... Ascites #Causes #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Algorithm #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... subclinical disease to acute ... liver failure ... regarding need for treatment ... #Management #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... Liver Failure ( ... ALF): • Liver ... liver #chemistry #diagnosis ... #differential #Hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... : - Acute kidney ... - Multiorgan failure ... #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
, eosinophilic fasciitis ... Inherited marrow-failure ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Acute Recurrent Pericarditis
= recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
effusion, Early failure ... manifestations, eosinophilia ... #Pericarditis #diagnosis ... #management #treatment ... #rheumatology #