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management differential hepatology dermatology causes rheumatology syndrome systemic gastroenterology infectiousdiseases injury pruritus secondary cirrhosis classification comparison druginduced fungal generalized hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... toxic aetiology: Skin ... non-essential drug/HDS treatments ... disease, Hepatic ... #Algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... disease 6-9 mo ... gastroenterology #algorithm ... gastroenterology #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... disease, liver ... Injury (DILI) ... gastroenterology #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... • Iatrogenic: DILI ... • NASH, Chronic ... #algorithm #hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Algorithm Low ... Renal Disease, Liver ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... : • Acute or Chronic ... disorders • Celiac disease ... effect following treatment
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... Algorithm - Systemic ... • Cholestatic liver ... disease Creatinine ... & BUN: • Chronic
Differential Diagnosis and Evaluation of Hyponatremia: 1) Identification of onset (acute vs. chronic) 2) Presence of symptoms (HA,
onset (acute vs. chronic ... status (edema, JVD, skin ... history (cardiac, liver ... , renal disease) ... #Differential #Algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... disease: > 2 ... • NASH, Chronic ... injury: > 3 • Chronic ... #chemistry #diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
- Differential Diagnosis ... Algorithm Endocrine ... Renal Failure • Liver ... Neoplastic / Hematologic ... Obstructive Pulmonary Disease
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