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rheumatology management differential dermatology druginduced syndrome systemic activation arthritis causes clues comparison dil disease disorders eosinophil eosinophilia laboratory macrophage muscle
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Manifestations: Malar rash ... • Immunologic Workup ... life-threatening • Treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... rash • Erythematous ... Differential Diagnosis ... • Kidney biopsy ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... • Immunologic Workup ... Erythematosus ( ... • Immunologic Workup ... #diagnosis #management
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... when infection has ... #diagnosis #sle ... clues #system #erythematosus ... #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... may be indicated ... consider tissue biopsy ... #Differential #diagnosis ... #hematology #eosinophilia
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... Petechial or purpuric rash ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... Autoimmune Vasculitis (lupus ... deficiency Work ... cryoglobulins • Skin biopsy
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... ’s syndrome - Lupus ... : - Biopsy - Microscopic ... Treatment: - Systemic
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
GBS), systemic lupus ... erythematosus ( ... SLE), polymyositis ... Atorvastatin Diagnosis ... IMNM) • Muscle biopsy
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus ( ... (to support a diagnosis ... #diagnosis #testing
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