17 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... symptoms of liver disease ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... obstruction - Drug-Induced ... hepatitis - Wilson disease ... #Differential # ... Hepatology #Diagnosis
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... Non-accidental Injury ... #Limping #NWB #Algorithm ... #Peds #Pediatrics ... #Diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Differential Diagnosis ... HELLP, Celiac disease ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... disorders • Celiac disease ... following EtOH induced ... #Diagnosis #Algorithm ... #Causes #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... • Cholestatic disease ... • Others #LFTs ... Diagnosis #Algorithm ... #Causes
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Diagnosis Algorithm ... Hemochromatosis • Wilson's Disease ... Hepatitis • Drug Induced ... #Diagnosis #Algorithm ... #Causes #Hepatology
Pediatric Dyspnea - Differential Diagnosis Algorithm
Stridor:
 • Croup
 • Foreign Body
 • Tracheitis
 • Epiglottitis
 •
Diagnosis Algorithm ... Body • Viral Induced ... Body • Heart Disease ... #Diagnosis #Algorithm ... #Causes #Peds #
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Diagnosis #Causes ... #Acute #algorithm ... #hepatology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Causes of Pleural ... Effusion - Differential ... Diagnosis Algorithm ... • Postcardiac injury ... #Algorithm #Hepatology