13 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... prevention (statin for CVA ... #CNS #neurology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... to 1:1 F:M • Clinical ... • Immunologic Workup ... Discontinuation of causal ... Evolution: Chronic disease
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... Evolution: Chronic disease ... Management #Summary #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic ... not required in all ... #Workup #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
RED FLAGS - In all ... cases there are ... suspicion of severe disease ... splenomegaly, abnormal neurology ... #Limping #NWB #Algorithm
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... approach to kidney disease ... Non-LN Kidney Disease ... Nephritis #diagnosis #algorithm ... #sle #nephrology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... rubella titer, ACE ... ANA and RF (if clinical ... Arthritis #laboratory #workup
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... heme (bleeding), CV ... Better call hematology ... #workup #hematology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
lupus cases, drug-dependent ... to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... #DIL #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... the underlying cause ... with AEDs until cause ... diagnosis #management #neurology