18 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... • Immunologic Workup ... months to years) Systemic ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Manifestations: Malar rash ... versus DIL • ... • Immunologic Workup
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
Maculopapular Rashes - THE ALGORITHMIC ... and systemic toxicity ... pathognomonic for SJS or EM ... #Diagnosis #Dermatology ... #Algorithm #Central
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... involvement 3% SLE-Related ... Lupusreference #SLE ... #Systemic #Lupus
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... fulminans - DIC ... deficiency Work ... #Algorithm #Causes
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... erythematosus (ACLE ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Erythematosus #Diagnosis
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... many differential diagnoses ... 6) An annular rash ... search ANA and aPL ... #sle #clues #system
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... genotypes): SS, SC, SE ... #Algorithm #workup ... #hematology #testing
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
coagulopathy (DIC ... petechial or purpuric rash ... While all patients ... #Diagnosis #Dermatology ... Purpural #Purpuric #Rash