10 results
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... hyperleukocytosis (AML ... - MH/CCF/CWRU EM ... #Differential #Diagnosis ... #Treatment #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Imaging: CXR- pulmonary ... #APML #diagnosis ... #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... aquagenic pruritis"), Hypertension ... transformation into AML ... • Treatment algorithms ... #treatment #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... ) on room air Treatment ... hepatopulmonary #syndrome ... #diagnosis #management ... #treatment #hepatology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diagnosis of ... irrigation • Management ... Inhibitors of Na+K+2Cl ... Torsemide) • Acute pulmonary ... Tolvaptan) • Treatment
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... : - Seen with AML ... (~20 %) and APL ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
- Remove all ... injury or after IM ... • Diagnosis: ... by bradycardia, hypotension ... #management #treatment
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... lipothymia, thirst, hypotension ... filling +++ (risk of pulmonary ... #diagnosis #management ... #rheumatology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
transformation into MDS or AML ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
myeloid leukemia (AML ... cytopenias and AML ... median age at diagnosis ... cardiovascular or pulmonary ... #algorithm #hematology