11 results
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid antibodies (aPL ... ): • Lupus anticoagulant ... Anticardiolipin antibodies (aCL ... of 1 clinical event ... #diagnosis #management
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... , others (RNP, aPL ... Anti-cardiolipin (aCl ... glycoprotein I (ß2GP), Lupus ... #diagnosis #associations
Lupus is diagnosed using clinical and laboratory diagnostic criteria set by the American College of Rheumatology.
Lupus is diagnosed ... using clinical ... A diagnosis of lupus ... #SLE #Lupus #Erythematosus ... #Criteria #ACR
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... thiazidic, PPI, ACE ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... (for secondary APS ... Erythematosus #SLE ... #management #treatment
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... pericarditis • Hematologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... erythematosus (ACLE ... Differential Diagnosis ... Chronic B-cell activation
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
complex → plt activation ... : • Clinical Suspicion ... Confirmatory test ↑Se ... D/c all heparin ... #Hematology #HemeOnc
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... cytokines, such as ... erythematosus [SLE ... #Syndrome #Diagnosis ... #Management #Hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... rubella titer, ACE ... (to support a diagnosis ... ANA and RF (if clinical ... laboratory #workup #diagnosis