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rheumatology sle differential erythematosus systemic treatment barre disease druginduced guillain hepatology monoclonal nephrology oncology workup abnormal activation algorithm anticoagulation antiphospholipid
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... least 2 joints • Neurologic ... pericarditis • Hematologic ... Erythematosus #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... ): • Lupus anticoagulant ... Anticardiolipin antibodies (aCL ... at least: • 1 clinical ... #management #anticoagulation
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... erythematosus (ACLE ... Differential Diagnosis ... Clinical Features ... Erythematosus #Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... Clinical Presentation ... SJIA], systemic lupus ... #Diagnosis #Management ... #Hematology #Rheumatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... Neurologic-Centered ... Features: POEMS, AL ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Evans • ITP • Cl-NH ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
brain PRES Clinical ... may precede the neurologic ... circulation: MCA ACA ... #diagnosis #management ... #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
complete paralysis of all ... Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... #diagnosis #management ... #treatment #neurology
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