31 results
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... ) = {Na - (Cl + ... - Diarrhea - Renal ... Diagnosis #Summary #Nephrology ... #differential
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #medications #druginduced
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup

NAGMA
- Chem, ABG or VBG
- Calculate Anion
Acidosis (NAGMA) - Differential ... NAGMA - Chem, ABG ... or VBG - Calculate ... Metabolic #NAGMA #Differential ... Diagnosis #Workup #nephrology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Injury • Pre-Renal ... @kdjhaveri #DrugInduced ... #KidneyInjury #differential ... diagnosis #algorithm #nephrology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
OTCs, herbals, abx ... - Urine Na/K/Cl ... protein/Cr - Renal ... AcuteKidneyInjury #AKI #Nephrology ... Algorithm #Causes #Differential
Urine Anion Gap in NAGMA
NA + K - Cl = surrogate for Urine NH4+
NH4+ is excreted
NAGMA NA + K - Cl ... excreted with Cl ... increasing negative AG ... RTA (nb ↑K) - Renal ... NAGMA #diagnosis #differential
Immunosuppression in Transplantation
Induction (I):
 - Basiliximab (Simulect)
 - Alemtuzumab (Campath)
 - Rituximab
 - Anti-Thymocyte Globulin (ATG)
Induction
Anti-Thymocyte Globulin (ATG ... #Medications #Pharmacology ... Maintenance #Management #Nephrology ... #Renal
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... testing: anti-ANCA ab ... , anti-GBM ab, ANA ... #Syndrome #differential ... #diagnosis #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... syndrome - Na-K-2Cl ... receptor Distal renal ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... • High Urine Cl ... hyperaldosteronism • High PRA: Renal ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology