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management druginduced leukemia lupus associations autoantibodies cardiology cardiomyopathy chronic cll comparison differentiation dil hyperkalemia k lymphocytic mds myelodysplasia myelodysplastic nephrology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... , others (RNP, aPL ... Autoantibodies #Rheumatology ... #table
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... sepsis), PE, DAH, CHF ... Renal Failure Treatment ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Score • CML -> AML ... Lymphadenopathy AML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
thiazidic, PPI, ACE ... life-threatening • Treatment ... #comparison #table ... #rheumatology # ... diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... phenomenon CLL Diagnosis ... microglobulin Treatment ... #workup #oncology ... #hematology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Medications: K+, ACEi ... Na delivery): CHF ... and Elimination (see ... Table below) ... Ca-gluconate or 1g CaCl
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... progression to AML ... factors (examples: G-CSF ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
May have typical HF ... orthopnea, PND, LE ... • Avoid ARB/ACE-I ... GDMT meds (e.g., ACE ... management #cardiology #treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... thiazidic, PPI, ACE ... constitutional symptoms • Treatment ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment
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