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diagnosis nephrology differential hyperkalemia potassium barre causes diuresis diuretics foamed gitelman guillain high pharmacology table tls tumor cardiology clinical encephalopathy
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Diagnosis Algorithm ... Transcellular Shift: • Alkalosis ... anemia) • G-CSF ... • Refeeding syndrome ... #nephrology #low
Treatment of hyperkalemia via kaliuresis step 1 = volume resuscitation if hypovolemic step 2 = consider fludrocortisone step
Treatment of hyperkalemia ... #kaliuresis #management ... #criticalcare # ... #diuresis #nephrology ... #algorithm
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... 6L/day) • For hyperkalemia ... #Syndrome #TLS ... #oncology #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... organ damage • Treatment ... hydration - Hyperkalemia ... treatment (no calcium ... #diagnosis #management
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... release due to cell lysis ... reaction - Tumor lysis ... syndrome - Rhabdomyolysis ... Food - Avoid in CRF
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Acidosis, Cell Lysis ... Na delivery): CHF ... acidosis), CK+LDH (lysis ... Ca-gluconate or 1g CaCl ... #nephrology #K
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... release due to cell lysis ... reaction - Tumor lysis ... syndrome - Rhabdomyolysis ... Food - Avoid in CRF
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Decompensated CHF ... Abdominal compartment syndrome ... Differential #Diagnosis #criticalcare ... #algorithm #treatment ... #management
The rationale for aggressive treatment of generalized status epilepticus was described previously here. In short,
for aggressive treatment ... cause aspiration, hyperkalemia ... #Management #Neurology ... #CriticalCare # ... Refractory #Seizures #Algorithm
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
hypomagnesemia • Metabolic alkalosis ... Hypochloremic metabolic alkalosis ... Rhabdomyolysis Treatment ... #diagnosis #nephrology ... #management #pathophysiology
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