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syndrome rheumatology toxidromes anticholinergics apml cold differential differentiation druginduced encephalopathy hyperthermic hypnotics leukostasis lupus lysis neurology oncology opioids posterior pres
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins. There are 5
syndrome (set of symptoms ... - Cholinergic: ACh ... antihistamines #Diagnosis ... #Toxicology #Toxidromes ... #Comparison #Table
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
and duration of symptoms ... angioedema Other symptoms ... doi: 10.1111/all ... #rheumatology # ... comparison #table
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... opacities • Diagnosis ... : >3 symptoms, or ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... circulation: MCA ACA ... Seizures: Treat with AEDs ... #management #neurology
Hyperthermic Toxidromes Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures. • Sympathomimetic -
of muscarinic Ach ... serotoninergic meds ... Hyperthermic #Toxidromes #comparison ... #table #diagnosis ... #differential #toxicology
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