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differential causes liver management lfts aclf alcoholic chronic cirrhosis dili druginduced eosinophilia erythematosus extravascular failure gastroenterology hemolysis hepatocellular intravascular liverenzymes
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... Drug-Induced liver injury ... - Autoimmune ... #Differential #Hepatology ... #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... Infectious: • Acute ... effect following treatment ... #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Algorithm Peripheral ... → Refer to hematology ... Rebound effect from treatment ... #Algorithm #hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... #algorithm #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... pattern of liver injury ... , AIH diagnosis ... #Hepatitis #AIH ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... dechallenge • Acute ... steatosis • Autoimmune ... #Diagnosis #Algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Algorithm Severe ... • Ischemia • Autoimmune ... • Drugs • AIH ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... • Infections: Hepatitis ... Other: NAFLD, Autoimmune ... #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular ... : Autoimmune hepatitis ... #diagnosis #algorithm ... #hepatology
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