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diagnosis hematology differential disease management classification cryoglobulinemia oncology signs symptoms workup activation agglutinin algorithm anemia antiphospholipid apls arterial behcet behcets
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
not related to clinical ... CRYOGLOBULINEMIA (type l) : Vascular ... Hyperviscosity syndrome ... and Ill) • Vascular ... #Diagnosis #Rheumatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Uveitis or retinal vasculitis ... Abnormal pathergy test ... Most Common Clinical ... and peripheral vascular ... Diagnosis #criteria #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... association • M > F Clinical ... and diplopia) • Vascular ... (Clinical Dx). ... signs #symptoms #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Vascular Sludging ... Hyperviscosity Syndrome ... : • Clinical triad ... 20% Sjögren's syndrome ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and bullous or vesicular ... : • Behçet Syndrome ... • Cogan Syndrome ... retinopathy Lab Tests ... differential #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... • Goodpasture syndrome ... #Dermatologic ... rash #diagnosis #rheumatology
Clinical Manifestations of Serotonin Syndrome • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements) • Gastrointestinal: Diarrhea,
Clinical Manifestations ... of Serotonin Syndrome ... sounds, RUQ pain • Dermatologic ... Clonus (inducible), Muscular ... Hyperthermia UCSD
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular ... Vasculitis) Autoantibodies ... (Thrombosis in vascular ... Paraproteinemias #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... Diagnosis #Management #Hematology ... #Rheumatology
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