ACLTear diagnosis peds hematology signs physicalexam msk symptoms dermatology syndrome leukemia

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Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear

rapid onset of symptoms ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis

Aplastic Anemia - Illness Script
Signs and symptoms:
• Recurrent infections from neutropenia
• Mucosal bleeding from

Illness Script Signs ... and symptoms: ... Symptomatic anemia Diagnosis ... to MDS or acute leukemia ... management #treatment #hematology

Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
• Lymphocytes accumulate in large numbers

with no early symptoms ... Physical Exam/Signs ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology

Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed

Episcleritis Signs ... and Symptoms: ... , breast CA - Hematologic ... cutis Diagnosis ... #diagnosis #dermatology

Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present

Stevens-Johnson Syndrome ... Staphylococcal scalded skin syndrome ... differentiating between the diagnosis ... #TEN #Dermatology ... #PhysicalExam #

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Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
• Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity

Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology

Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells

- Differential Diagnosis ... pattern of spread, B symptoms ... Treated Like Acute Leukemias ... Amy Chung, MD, MSc ... pathophysiology #Hematology

Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
- DDX:
-

- Differential Diagnosis ... Effusions: - Hematologic ... - Leukemia ... #differential #diagnosis ... #msk #physicalexam

Clinical features of Liver Disease in Children

#Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings #Diagnosis #Peds #Pediatrics #Hepatology

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#LiverFailure #Signs ... #Symptoms #PhysicalExam ... #Findings #Diagnosis ... #Peds #Pediatrics ... #Hepatology

Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
• Young

meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... tears, Ischemia, Leukemia ... #signs #symptoms ... #rheumatology #

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