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diagnosis hematology algorithm lymphadenopathy diffuse generalized localized pruritus systemic cd4 icl idiopathic leukemia lymphocytopenia lymphopenia mds myelodysplasia primary syndromes
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Neoplastic (Leukemia, Lymphoma ... ) #Diffuse #Focal ... Lymphadenopathy #LAD ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Tularemia • Secondary ... #Localized #Focal ... Lymphadenopathy #LAD ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Non-Hodgkin's Lymphoma ... • Hodgkin's Lymphoma ... Lymphadenopathy #LAD ... #Hematology #Oncology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... : • Lymphoma ... Throbocythemia • Myelodisplastic ... Pruritus #primary #secondary ... #generalized #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... compounds, alcohol, lead ... blood count with differential ... #oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
: • Lymphoma ... Throbocythemia • Myelodisplastic ... #Pruritus #secondary ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
underlying primary or secondary ... Unc119) • Heme (lymphoma ... . aplasia/myelodysplasia ... #Differential # ... Causes #lymphocytopenia
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