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diagnosis differential rheumatology neurology management algorithm causes acr2021 gravis clinical vasculitis physicalexam treatment guidelines ophthalmology pharmacology ptosis ocular video lupus
Drugs associated with worsening of Myasthenia Gravis (MG): • D-penicillamine • Botulinum toxin. • Telithromycin • Fluoroquinolones • Quinine • Magnesium • Macrolide antibiotics • Corticosteroids (may cause transient
with worsening of Myasthenia ... of generalized AChR-MG ... prevent prolonged myasthenic ... higher risk of myasthenic ... muscle-specificreceptortyrosinekinase #AChR
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... Overview Myasthenia ... Ab to AChR blocks ... arthritis, SLE Myasthenia ... Labs: - AchR antibodies
Ice-pack Test for Myasthenia Gravis - Likelihood Ratio (LR) +24 / -0.16 Ice pack's can be used
Ice-pack Test for Myasthenia ... effectively increasing ACh ... Icepack #Test #Myasthenia
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... Myasthenia gravis ... suspected and anti-ACh ... Seronegative ocular myasthenia ... eyelid #Ocular #Myasthenia
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 Myasthenia Gravis - Ptosis, Diplopia, Blurred Vision Acute Myasthenic Crisis • Triggered by infection, medication • Respiratory
Myasthenia Gravis ... Vision Acute Myasthenic ... ventilation #Myasthenia
Central Nervous System Pharmacology - Somatic and Autonomic Receptors Somatic • Rocuronium -> Non-depolarizing (reversible competitive inhibitors)
blocks action AchE ... the levels of Ach ... and Digest” - Ach ... Fight or Flight” - Ach ... Adrenal Medulla - Ach
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic
Myasthenia Gravis Signs, Symptoms and Testing - Likelihood Ratios Does this patient have myasthenia gravis? JAMA. 2005 Apr 20;293(15):1906-14.
Myasthenia Gravis ... this patient have myasthenia ... #Diagnosis #Myasthenia
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... MuSK-positive myasthenia ... mild generalized myasthenia ... weakness and in myasthenic ... SinaiBmoreIMRes #Myasthenia
Curtain Sign - Enhanced Ptosis in Myasthenia Gravis Because of bilateral eyelid innervation, when the more affected
Enhanced Ptosis in Myasthenia ... Enhanced #Ptosis #Myasthenia
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