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diagnosis differential rheumatology causes algorithm management sle erythematosus neurology clinical treatment systemic nephrology symptoms classification signs vasculitis dermatology pathophysiology pharmacology
Drugs associated with worsening of Myasthenia Gravis (MG): • D-penicillamine • Botulinum toxin. • Telithromycin • Fluoroquinolones • Quinine • Magnesium • Macrolide antibiotics • Corticosteroids (may cause transient
with worsening of Myasthenia ... of generalized AChR-MG ... prevent prolonged myasthenic ... higher risk of myasthenic ... muscle-specificreceptortyrosinekinase #AChR
Myasthenia Gravis - Ptosis, Diplopia, Blurred Vision Acute Myasthenic Crisis • Triggered by infection, medication • Respiratory
Myasthenia Gravis ... Vision Acute Myasthenic ... ventilation #Myasthenia
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... Overview Myasthenia ... Ab to AChR blocks ... arthritis, SLE Myasthenia ... Labs: - AchR antibodies
Diagnostic Criteria for Systemic Lupus Erythematosus - ACR and SLICC Criteria #Diagnosis #Rheumatology #SLE #Lupus #Erythematosus #Criteria
Criteria for Systemic Lupus ... Erythematosus - ACR ... Rheumatology #SLE #Lupus ... Erythematosus #Criteria #ACR
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 Ice-pack Test for Myasthenia Gravis - Likelihood Ratio (LR) +24 / -0.16 Ice pack's can be used
Ice-pack Test for Myasthenia ... effectively increasing ACh ... Icepack #Test #Myasthenia
Central Nervous System Pharmacology - Somatic and Autonomic Receptors Somatic • Rocuronium -> Non-depolarizing (reversible competitive inhibitors)
blocks action AchE ... the levels of Ach ... and Digest” - Ach ... Fight or Flight” - Ach ... Adrenal Medulla - Ach
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic Lupus ... cutaneous or discoid lupus ... Acute cutaneous lupus ... Class II or V lupus
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... Myasthenia gravis ... suspected and anti-ACh ... Seronegative ocular myasthenia ... eyelid #Ocular #Myasthenia
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 Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic
Myasthenia Gravis Signs, Symptoms and Testing - Likelihood Ratios Does this patient have myasthenia gravis? JAMA. 2005 Apr 20;293(15):1906-14.
Myasthenia Gravis ... this patient have myasthenia ... #Diagnosis #Myasthenia
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