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Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table

Diabetes Insipidus - Inadequate ADH
SIADH -
Inappropriate ADH ... ) - Comparison Table ... SIADH - Excess ADH ... SIADH #Comparison #Table ... #Pathophysiology
Thiazide induced Hyponatremia - Pathophysiology
 • Reduced distal delivery
 • Inhibition of the NCC (dilution capcity)-
Hyponatremia - Pathophysiology ... permeability increased - ADH ... independent / ADH ... #Hyponatremia #Pathophysiology
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Inappropriate ADH ... insufficiency ADH ... Differential #Diagnosis #Table ... #Causes #Sodium
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... antagonists 6) ADH ... Adenosine #Nephron #Pathophysiology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Inappropriate ADH ... physiologic stimulus to ADH ... 100 mmol/kg - ADH ... Diagnosis #Algorithm #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Inappropriate ADH ... physiologic stimulus to ADH ... 100 mmol/kg - ADH ... Diagnosis #Algorithm #Causes
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Insipidus (Decr ADH ... Insipidus (Incr ADH ... Differential #Diagnosis #Table ... #Causes
Causes of AKI in Pregnancy - Differential Diagnosis
Creatinine - Platelets - Transaminases - LDH - PT/PTT
Causes of AKI in ... Transaminases - LDH ... Differential #Diagnosis #Causes ... #table
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
electrolyte abnormality caused ... among the possible causes ... lower than 80% in cases ... in blood urea causes ... Circulating ADH
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... Ineffective (UNa >30) • ADH ... Salt Wasting • ADH ... intake, UNa <20) • ADH ... differential #diagnosis #table