9 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... and Anticoagulant ... twitter.com/AmyChung #AntiCoagulation ... #Cascade #Anticoagulants ... Mechanisms #DOAC #Hematology
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... on Coagulation ... Tests PT / INR, aPTT ... EricsMedicalLectures/ #Anticoagulants ... #Tests #Anticoagulation
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... Patient Receiving Anticoagulants ... ISNeducation #Abnormal ... #APTT #prolonged ... #diagnosis #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... inhibitor and lupus anticoagulant ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... deficiency • Anticoagulant
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... heparin - Other anticoagulants ... Jcortesizaguirr #Abnormal ... #differential #hematology ... #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia - Normal ... Reduction of pro/anticoagulants ... INR < 2.3 - APTT ... < 1.5 x normal ... treatment #management #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... #Coagulation #Cascade ... thrombin #clot #PT #PTT ... pathophysiology #anticoagulation ... #anticoagulant
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... #doac #noac #anticoagulation ... #hematology #laboratory ... #testing #aptt
Management of Jehovah's Witness patient in ICU 

Clarify which products may be used 
 - Discuss
coagulopathy - Avoid anticoagulants ... - When anticoagulation ... - Be aware of coagulation ... platelets, INR, PTT