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diagnosis hematology differential management oncology algorithm hemeonc leukemia lymphocytic workup atlas blood bloodcell common cvid hemolytic hemophagocytic hlh hypogammaglobulinemia immunodeficiency
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- CD7, CD3 Chronic ... - Abnormal morphology ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... #hematology #Markers
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology ... , Chronic disease ... Unstable hemoglobin disorders ... BloodCell #RBC #Morphology ... differential #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... lymphoproliferative disorders ... • Neutropenia, anemia ... , thrombocytopenia ... #Chronic #Lymphocytic
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... 5) Symptoms of anemia ... or thrombocytopenia ... or thrombocytopenia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... other reproducible morphologic ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... platelet count (thrombocytopenia ... Marrow Failure • Chronic ... IDUS) • Immune Thrombocytopenia ... Neutropenia • Platelet Disorders
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to impaired B-cell ... Autoimmunity • Chronic ... specifically immune thrombocytopenia ... autoimmune hemolytic anemia
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Hemophagocytic Lymphohistiocytosis ... - Cytopenias (anemia ... , thrombocytopenia ... malignancy, autoimmune disorder ... Hemophagocytic #Lymphohistiocytosis
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