25 results
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... diagnosis of drug-induced ... patients with drug-induced ... #Diagnosis #Hematology ... #Differential #
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
• Thrombotic Thrombocytopenic ... TMA - Drug-induced ... Metabolism-mediated TMA - Coagulation-mediated ... Microangiopathy #TMA #hematology ... #differential #
Drugs Commonly Implicated as Triggers of Drug Induced Thrombocytopenia
#Diagnosis #Hematology #Thrombocytopenia #Differential #DrugInduced #Medications
Triggers of Drug Induced ... Thrombocytopenia ... #Diagnosis #Hematology ... #Thrombocytopenia ... #Differential #
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... thrombin time • Reduced ... , V and II • Reduced ... Fibrinogen: ↓ • PT ... treatment #management #hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged PT ... • Prolonged PT ... #INR #Differential ... Algorithm #Causes #Hematology ... #coagulation #disorders
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
Post-Partum Hemorrhage - Differential ... e.g. prolonged/induced ... intravascular coagulation ... (DIC) • Anti-coagulation ... Hemorrhage #PPH #Differential
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... thrombin → thrormbin-induced ... platelet aggregation PT ... using INR use PT ... Scoring #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Diagnosis Algorithm Thrombocytopenia ... • Vasculitis Coagulation ... Bleeding #Bruising #Differential ... Algorithm #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... TMA: Unexplained thrombocytopenia ... antiglobulin test, PT ... hemosiderin • PT ... Management #Algorithm #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Congenital intrinsic coagulation ... Reduced liver synthesis ... intravascular coagulation ... Causes #diagnosis #differential ... #hematology #coagulation