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diagnosis hematology differential management oncology dermatology elevatedmcv intravascular macrocytosis product reactions workup aplastic approach cirrhosis classification coagulation dic disorders disseminated
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... the peripheral blood ... purpura/hemolytic ... , Hematology 2012 ... #Differential #Algorithm
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... : - Thrombocytopenia ... • Secondary Causes ... - Hemolytic anemia ... Differential #Diagnosis #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Differential Diagnosis Algorithm ... Blood Loss: >500mL ... purpura (ITP) ... purpura (TTP)
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Heart Valve) #Thrombocytopenia ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... plateletcount), peripheral blood ... changes), high MCV anemia ... of thrombocytopenia ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... Extravascular #Causes ... #anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Differential Diagnosis Algorithm ... Blood Loss ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Treat primary cause ... Coagulation #diagnosis #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... hemostasis: - Thrombocytopenia ... : • Complete blood ... • Fecal occult blood
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