15 results
diagnosis hematology management differential oncology intravascular product reactions workup alkaline alp aplastic arterial ascorbicacid cirrhosis coagulation dermatology dic disorders disseminated
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... : - Thrombocytopenia ... • Secondary Causes ... - Hemolytic anemia ... Differential #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... plateletcount), peripheral blood ... changes), high MCV anemia ... of thrombocytopenia ... #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Treat primary cause
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... Extravascular #Causes ... #anemia
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... result in severe anemia ... of Peripheral blood ... immune hemolytic anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... skin that are caused ... Out Secondary Causes ... IDUS) • Immune Thrombocytopenia ... Syndromes #diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Heparin-induced thrombocytopenia ... coagulation and other causes ... of purpura fulminans ... Venous #Arterial #pathophysiology ... #hematology #differential
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
breath, wasting, anemia ... Loss of teeth Anemia ... cutaneous vasculitis, thrombocytopenia ... , or any other cause ... #AscorbicAcid #Pathophysiology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... infections/fevers • Thrombocytopenia ... and petechiae Causes ... result from low blood ... #oncology #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... RETIC INDEX: • Blood ... splenomegaly, Thrombocytopenia ... syndrome, Spur cell anemia ... Differential #Diagnosis #Hepatology
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