18 results
A cirrhosis tweetorial all about the platelet

Aims:
- Identify cirrhosis based on blood tests- 
- Understand why
A cirrhosis tweetorial ... Aims: - Identify cirrhosis ... #coagulopathy ... CBC #Tweetorial #Hepatology ... #Pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... protein C and S Pathophysiology ... or consumption coagulopathy ... #Coagulation #diagnosis ... treatment #management #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
- Differential Diagnosis ... Microangiopathy: DIC ... sequestration: - Cirrhosis ... #Differential #Diagnosis ... #Framework #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
intravascular coagulopathy ... (DIC) #RBC #Morphology ... #Atlas #key #diagnosis ... #differential #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... rapidly develops (DIC ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver failure with coagulopathy ... DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... #differential #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... leukocytosis and coagulopathy ... opacities • Diagnosis ... PCC to reverse coagulopathy ... #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... 65 years PBC Pathophysiology ... cholestasis → Cirrhosis ... Differential Diagnosis ... #workup #hepatology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
- Differential Diagnosis ... Collapse: • Pathophysiology ... cardiomyopathy, ARDS, DIC ... Findings: - Mild coagulopathy ... - Possible DIC
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
regarding the diagnosis ... Patients with cirrhosis ... with elevated HIC ... hemochromatosis #algorithm #diagnosis ... #management #hepatology