24 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... collection with EDTA Pathophysiology ... , ↓ALPLow ... mineralization Symptoms ... respiratory failure • Neurologic
Aqueous Humor Production and Drainage
 • Provides nutrition, removes wastes, and transports neurotransmitters to the avascular
10-21 mmHg) AH ... ) -> AH passes through ... ) -> AH enters uveal ... #Pathophysiology ... #ophthalmology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Reduced renal blood flow ... • Increased AVP ... syndrome #Mechanisms #pathophysiology ... #nephrology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
lymphocyte predominant (LP ... pattern of spread, B symptoms ... B-Cell ~90% • Low ... Grade - Slow growing ... Classification #pathophysiology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
weight loss - Low ... disturbances: low ... PO4 -> decr RBC ATP ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Abnormal blood flow ... narrowing • Slow ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
inflammation of all ... Orbital #Cellulitis #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
produces them when low ... precipitant. 5) treat low ... resolves due to ATP ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... (1) limb-onset ALS ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology